Universal search bar

Type the location in a genome with chromosome and position, or the gene symbol. For example chr5:148,451,032 or NF2. The search bar will quickly find and take you there.

Bird's-eye view

See more of the genome at a glance than ever before. With C# rendering there's no worry about limiting your visibility to a limited local region. Gain insights from overall alignment topology and patterns that were previously unseen. Pinch to zoom.

Scroll with gestures

Move through sequences at speed using the gestures on your trackpad or mouse. Use the keyboard arrows to move single nucelotides or fly through thousands of bases at a time with momentum scrolling. Hold ⌘ symbol with a direction to jump to nearest potential variant, without a VCF.

Quickly load files

Even large BAM files from high coverage projects and reference genomes open quickly. Thanks to efficient in-memory file streams and background threads, you won't have to worry about freeze-ups or sit around waiting to work.

Stream remote data

Load remote .bam and .fasta data using multiple protocols. Use the universal search bar to just type in the remote address of your files, and they will be streamed and rendered as needed. No need to keep a bunch of external drives with large files.

Push notifications

Stay in the know, when updates are available you will be the first to get them. So new features and bug fixes are easily rolled out, without email lists or you having to check the web.

Quality metrics

Real-time read qualities are displayed at any location you happen to be, cycling through the entire pileup. Zoom in to nucleotide level to see the quality of each individual base sequenced.

Bookmarks & more

Our favorite hidden features like bookmarks, lets you save and organize important locations, like on the web. There's even scripting to implement custom features, and just in case you don't like the color scheme, that's customizable as well.

Alignments

Lucid assumes your files meet the SAM/BAM format specifications. All alignments should be in a .bam file with an index .bam.bai file in the same directory. Files can be local or remote, and made by any algorithm as long as the output adheres to these specifications.

Reference Genomes

References are displayed along the top of Lucid, and should be in FASTA format (.fa or .fasta). The fasta index file in .fasta.fai should be in the same local or remote directory as the reference file. Search/jump works best when one fasta contains the whole reference.

Reference nCoV2019

The reference genome assembly of the novel 2019 coronavirus can be downloaded or streamed from our servers at the following location:

https://lucidalign.com/download/
GCF_009858895.2_ASM985889v3_genomic.fa

Outbreak Alignment File

We are providing a sample alignment from the Washington outbreak. This BAM already has some variants with the reference, download or stream here:

https://lucidalign.com/download/
SARS-CoV-2_align_sorted.bam

Demo Alignment File

A .bam file made using best practices and hosted on our server, can be streamed or downloaded.

http://lucidalign.com/download/demo_align.bam

Human Reference Files

This is a great reference by the Broad Institute, often used for human analysis.

http://lucidalign.com/download/
Homo_sapiens_assembly19.fasta

Ensembl Species

Try out the sequencing data from more species than you can shake a stick at.

 ftp://ftp.ensembl.org/pub/current_bamcov

Human NA12878 Files

These are GIAB standardized samples. This location has files from most platforms.

ftp://ftp.ncbi.nih.gov/giab/ftp/data/NA12878